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Publications

• Radial glia progenitor polarity in health and disease
• Forebrain Eml1 depletion reveals early centrosomal dysfunction causing subcortical heterotopia
• Targeting pathological cells with senolytic drugs reduces seizures in neurodevelopmental mTOR-related epilepsy
• In Memoriam: Richard Miles: Neuroscience network has lost a key synapse
• PAK3 activation promotes the tangential to radial migration switch of cortical interneurons by increasing leading process dynamics and disrupting cell polarity
• CXCL12 targets the primary cilium cAMP/cGMP ratio to regulate cell polarity during migration
• A class-specific effect of dysmyelination on the excitability of hippocampal interneurons
• Hippocampal and neocortical BRAF mutant non-expansive lesions in focal epilepsies
• Grey matter heterotopia subtypes show specific morpho-electric signatures and network dynamics
• Self-organizing models of human trunk organogenesis recapitulate spinal cord and spine co-morphogenesis
• PYK2, a hub of signaling networks in breast cancer progression
• Operant training for highly palatable food alters translating mRNA in nucleus accumbens D2 neurons and reveals a modulatory role of Neurochondrin
• 5-HT1A and 5-HT2B receptor interaction and co-clustering regulate serotonergic neuron excitability
• BDNF/TrkB pathway activation in D1 receptor-expressing striatal projection neurons plays a protective role against L-DOPA-induced dyskinesia
• Role of purines in brain development, from neuronal proliferation to synaptic refinement
• Serotonin sensing by microglia conditions the proper development of neuronal circuits and of social and adaptive skills
• Adult-specific Reelin expression alters striatal neuronal organization: implications for neuropsychiatric disorders
• A human dynein heavy chain mutation impacts cortical progenitor cells causing developmental defects, reduced brain size and altered brain architecture
• Cognitive and Emotional Symptoms Induced by Chronic Stress Are Regulated by EGR1 in a Subpopulation of Hippocampal Pyramidal Neurons
• Differential impacts of Cntnap2 heterozygosity and Cntnap2 null homozygosity on axon and myelinated fiber development in mouse
• Lateral Diffusion of NKCC1 Contributes to Chloride Homeostasis in Neurons and Is Rapidly Regulated by the WNK Signaling Pathway
• Establishing Hedgehog Gradients during Neural Development
• DNA methylation and hydroxymethylation characterize the identity of D1 and D2 striatal projection neurons
• Conformational state-dependent regulation of GABAA receptor diffusion and subsynaptic domains
• First quantitative dosages: Strong correlations between non-5-HT2Rs serotonin receptors on normal human heart valves
• Targeting the brain 5-HT7 receptor to prevent hypomyelination in a rodent model of perinatal white matter injuries
• Silencing KCC2 in mouse dorsal hippocampus compromises spatial and contextual memory
• Primary Cilia Influence Progenitor Function during Cortical Development.
• Inflammation and Autophagy: A Convergent Point between Autism Spectrum Disorder (ASD)-Related Genetic and Environmental Factors: Focus on Aluminum Adjuvants.
• Plea for a Simple But Radical Change in Scientific Publication: To Improve Openness, Reliability, and Reproducibility, Let's Deposit and Validate Our Results before Writing Articles
• RAB6 and dynein drive post-Golgi apical transport to prevent neuronal progenitor delamination
• PYK2 senses calcium through a disordered dimerization and calmodulin-binding element
• Editorial: Functional Aspects of Mesoscopic Brain Oscillations: Insights From in vivo and in vitro Studies.
• How the brain gets rid of supernumerary synapses during development.
• Hippocampal Egr1-Dependent Neuronal Ensembles Negatively Regulate Motor Learning.
• Novel role of the synaptic scaffold protein Dlgap4 in ventricular surface integrity and neuronal migration during cortical development
• Visualising the cytoskeletal machinery in neuronal growth cones using cryo-electron tomography
• Doublecortin mutation leads to persistent defects in the Golgi apparatus and mitochondria in adult hippocampal pyramidal cells
• Human cerebral organoids reveal progenitor pathology in EML1-linked cortical malformation
• Pyk2 regulates MAMs and mitochondrial dynamics in hippocampal neurons.
• Synaptic inhibition in the lateral habenula shapes reward anticipation.
• Epilepsy related to focal neuronal lipofuscinosis: extra-frontal localization, EEG signatures and GABA involvement
• Translational profiling of mouse dopaminoceptive neurons reveals region-specific gene expression, exon usage, and striatal PGE2 modulatory effects.
• CADPS functional mutations in patients with bipolar disorder increase the sensitivity to stress.
• Heterozygous Dcc Mutant Mice Have a Subtle Locomotor Phenotype.
• Mouse modeling dissecting macrophage-breast cancer communication uncovered roles of PYK2 in macrophage recruitment and breast cancer growth.
• Mild stress accumulation limits GABAergic synaptic plasticity in the lateral habenula.
• The metabolic and redox signaling of the nucleoredoxin-like 2 gene supports brain function
• Gephyrin interacts with the K-Cl co-transporter KCC2 to regulate its surface expression and function in cortical neurons.
• Cell type- and region-specific modulation of cocaine seeking by micro-RNA-1 in striatal projection neurons.
• Convergence of adenosine and GABA signaling for synapse stabilization during development
• Brain neural patterns and the memory function of sleep.
• The non-receptor tyrosine kinase Pyk2 in brain function and neurological and psychiatric diseases.
• Lis1 mutation prevents basal radial glia-like cell production in the mouse.
• Ultrastructural Evidence for Oxytocin and Oxytocin Receptor at the Spinal Dorsal Horn: Mechanism of Nociception Modulation
• Pyk2 in dorsal hippocampus plays a selective role in spatial memory and synaptic plasticity.
• Dopamine D1 receptor-expressing neurons activity is essential for locomotor and sensitizing effects of a single injection of cocaine.
• Elevated expression of complement C4 in the mouse prefrontal cortex causes schizophrenia-associated phenotypes
• Dynamic extrinsic pacing of the HOX clock in human axial progenitors controls motor neuron subtype specification
• Serotonin 2B Receptor by Interacting with NMDA Receptor and CIPP Protein Complex May Control Structural Plasticity at Glutamatergic Synapses
• Dorsal raphe serotonin neurotransmission is required for the expression of nursing behavior and for pup survival
• DARPP-32 40 years later.
• In vitro models of spinal motor circuit's development in mammals: achievements and challenges.
• The Multifaceted Roles of KCC2 in Cortical Development
• Mapping the molecular and cellular complexity of cortical malformations
• Targeting 5-HT2B Receptor Signaling Prevents Border Zone Expansion and Improves Microstructural Remodeling After Myocardial Infarction
• International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function
• Long-lasting tagging of neurons activated by seizures or cocaine administration in Egr1-CreERT2 transgenic mice.
• Extracellular Control of Radial Glia Proliferation and Scaffolding During Cortical Development and Pathology
• YIF1B mutations cause a post-natal neurodevelopmental syndrome associated with Golgi and primary cilium alterations
• Neuronal migration and disorders - an update
• The serotonin 2B receptor is required in neonatal microglia to limit neuroinflammation and sickness behavior in adulthood
• An Etiological Foxp2 Mutation Impairs Neuronal Gain in Layer VI Cortico-Thalamic Cells through Increased GABAB/GIRK Signaling
• Molecular Crowding and Diffusion-Capture in Synapses.
• fMRI detects bilateral brain network activation following unilateral chemogenetic activation of direct striatal projection neurons.
• Direct Readout of Neural Stem Cell Transgenesis with an Integration-Coupled Gene Expression Switch.
• Astrocytic BDNF and TrkB regulate severity and neuronal activity in mouse models of temporal lobe epilepsy.
• A regulatory pathway linking caffeine action, mood and the diurnal clock.
• Regulation of microglia by neuromodulators: Modulations in major and minor modes.
• Functional and molecular heterogeneity of D2R neurons along dorsal ventral axis in the striatum.
• The non-receptor tyrosine kinase Pyk2 modulates acute locomotor effects of cocaine in D1 receptor-expressing neurons of the nucleus accumbens.
• Epigenetic tinkering with neurotransmitters.
• Serotonin (5-HT) Shapes the Macrophage Gene Profile through the 5-HT2B-Dependent Activation of the Aryl Hydrocarbon Receptor.
• How early life impacts emotional behaviour in adulthood.
• Dynamics and organization of proteins in the neuronal plasma membrane.
• Differential Membrane Binding and Seeding of Distinct α-Synuclein Fibrillar Polymorphs.
• Cation–chloride cotransporters and the polarity of GABA signalling in mouse hippocampal parvalbumin interneurons
• Long-term development of human iPSC-derived pyramidal neurons quantified after transplantation into the neonatal mouse cortex.
• Increased surface P2X4 receptor regulates anxiety and memory in P2X4 internalization-defective knock-in mice.
• The Ciliary Protein Arl13b Functions Outside of the Primary Cilium in Shh-Mediated Axon Guidance
• EML1-associated brain overgrowth syndrome with ribbon-like heterotopia.
• Exacerbation of C1q dysregulation, synaptic loss and memory deficits in tau pathology linked to neuronal adenosine A2A receptor.
• FIGNL1 associates with KIF1Bβ and BICD1 to restrict dynein transport velocity during axon navigation.
• Emerging Roles of Complement in Psychiatric Disorders.
• Genes and Mechanisms Involved in the Generation and Amplification of Basal Radial Glial Cells.
• TBR2 coordinates neurogenesis expansion and precise microcircuit organization via Protocadherin 19 in the mammalian cortex.
• Early-life stress impairs postnatal oligodendrogenesis and adult emotional behaviour through activity-dependent mechanisms.
• Mutations in the Heterotopia Gene Eml1/EML1 Severely Disrupt the Formation of Primary Cilia.
• KCC2 Regulates Neuronal Excitability and Hippocampal Activity via Interaction with Task-3 Channels.
• BMP4 patterns Smad activity and generates stereotyped cell fate organization in spinal organoids.
• Differential enhancement of ERK, PKA and Ca2+ signaling in direct and indirect striatal neurons of Parkinsonian mice.
• Morphine withdrawal recruits lateral habenula cytokine signaling to reduce synaptic excitation and sociability.
• Withdrawal: Discrepancy in insulin regulation between gestational diabetes mellitus (GDM) platelets and placenta
• Anticonvulsant and antiepileptogenic effects of system x−c inactivation in chronic epilepsy models.
• The neuroanatomy of Eml1 knockout mice, a model of subcortical heterotopia.
• Selective Axonal Expression of the Kv1 Channel Complex in Pre-myelinated GABAergic Hippocampal Neurons.
• Topographical cues control the morphology and dynamics of migrating cortical interneurons.
• Protein interacting with Amyloid Precursor Protein tail-1 (PAT1) is involved in early endocytosis.
• Cyclin-Dependent Kinase 5 Dysfunction Contributes to Depressive-like Behaviors in Huntington's Disease by Altering the DARPP-32 Phosphorylation Status in the Nucleus Accumbens.
• Boc Acts via Numb as a Shh-Dependent Endocytic Platform for Ptch1 Internalization and Shh-Mediated Axon Guidance
• The Shh receptor Boc is important for myelin formation and repair
• Genetic and pharmacological manipulation of glial glutamate transporters does not alter infection-induced seizure activity.
• ATP6AP2 variant impairs CNS development and neuronal survival to cause fulminant neurodegeneration.
• AUTS2 isoforms control neuronal differentiation.
• Rotatin' the phenotypes.
• Expression of Concern: Discrepancy in insulin regulation between gestational diabetes mellitus (GDM) platelets and placenta
• Enhanced Renewal of Erythroid Progenitors in Myelodysplastic Anemia by Peripheral Serotonin.
• KCC2 membrane diffusion tunes neuronal chloride homeostasis.
• Reciprocal Regulation of KCC2 Trafficking and Synaptic Activity.
• PKR knockout in the 5xFAD model of Alzheimer's disease reveals beneficial effects on spatial memory and brain lesions.
• Mice carrying a humanized Foxp2 knock-in allele show region-specific shifts of striatal Foxp2 expression levels.
• Two-photon Imaging of Microglial Processes' Attraction Toward ATP or Serotonin in Acute Brain Slices.
• Punishment-Predictive Cues Guide Avoidance through Potentiation of Hypothalamus-to-Habenula Synapses.
• Conditional BDNF Delivery from Astrocytes Rescues Memory Deficits, Spine Density, and Synaptic Properties in the 5xFAD Mouse Model of Alzheimer Disease.
• The Ciliopathy Gene Ftm/Rpgrip1l Controls Mouse Forebrain Patterning via Region-Specific Modulation of Hedgehog/Gli Signaling.
• RPGRIP1L is required for stabilizing epidermal keratinocyte adhesion through regulating desmoglein endocytosis.
• Dimers of serotonin receptors: Impact on ligand affinity and signaling.
• Pyk2 in the amygdala modulates chronic stress sequelae via PSD-95-related micro-structural changes.
• Clustering of Tau fibrils impairs the synaptic composition of α3-Na+/K+-ATPase and AMPA receptors.
• Somato-Dendritic Regulation of Raphe Serotonin Neurons; A Key to Antidepressant Action.
• Ghrelin and food reward.
• A positive association between a polymorphism in the HTR2B gene and cocaine-crack in a French Afro-Caribbean population.
• GLS1 Mutant Mice Display Moderate Alterations of Hippocampal Glutamatergic Neurotransmission Associated with Specific Adaptive Behavioral Changes.
• CNTNAP2 Heterozygous Missense Variants: Risk Factors for Autism Spectrum Disorder and/or Other Pathologies?
• Serotonin in retina.
• Frontiers of Serotonin Beyond the Brain.
• Altered social behavior in mice carrying a cortical Foxp2 deletion.
• SSRIs target prefrontal to raphe circuits during development modulating synaptic connectivity and emotional behavior.
• Regulation of raphe serotonin neurons by serotonin 1A and 2B receptors.
• Evolutionary considerations on 5-HT2 receptors.
• Adiporon, an adiponectin receptor agonist acts as an antidepressant and metabolic regulator in a mouse model of depression.
• The Barnes Maze Task Reveals Specific Impairment of Spatial Learning Strategy in the Intrahippocampal Kainic Acid Model for Temporal Lobe Epilepsy.
• Lateral Habenula Gone Awry in Depression: Bridging Cellular Adaptations With Therapeutics.
• Polarized Dock Activity Drives Shh-Mediated Axon Guidance
• Translational studies support a role for serotonin 2B receptor (HTR2B) gene in aggression-related cannabis response.
• Microtubule architecture in vitro and in cells revealed by cryo-electron tomography.
• PTK2B/Pyk2 overexpression improves a mouse model of Alzheimer's disease.
• Genetic variants in autism-related CNTNAP2 impair axonal growth of cortical neurons.
• Constraints on somatosensory map development: mutants lead the way.
• Genetic deletion of xCT attenuates peripheral and central inflammation and mitigates LPS-induced sickness and depressive-like behavior in mice.
• Inhibition of astroglial connexin43 hemichannels with TAT-Gap19 exerts anticonvulsant effects in rodents.
• Hedgehog: A Key Signaling in the Development of the Oligodendrocyte Lineage
• Cortical progenitor biology: key features mediating proliferation versus differentiation.
• In Vitro Models to Analyze the Migration of MGE-Derived Interneurons.
• Sequences Flanking the Gephyrin-Binding Site of GlyRβ Tune Receptor Stabilization at Synapses.
• Tubulin diversity and neuronal migration.
• Positive regulation of raphe serotonin neurons by serotonin 2B receptors.
• Activity-Dependent Inhibitory Synapse Scaling Is Determined by Gephyrin Phosphorylation and Subsequent Regulation of GABAA Receptor Diffusion.
• Microglia Gone Rogue: Impacts on Psychiatric Disorders across the Lifespan.
• Functional Principles of Posterior Septal Inputs to the Medial Habenula.
• Cocaine conditioned place preference: unexpected suppression of preference due to testing combined with strong conditioning.
• Eml1 loss impairs apical progenitor spindle length and soma shape in the developing cerebral cortex.
• A Simple and Powerful Analysis of Lateral Subdiffusion Using Single Particle Tracking.
• GABAA receptor dependent synaptic inhibition rapidly tunes KCC2 activity via the Cl--sensitive WNK1 kinase.
• Nicotinic receptors mediate stress-nicotine detrimental interplay via dopamine cells' activity.
• 6 Hz corneal kindling in mice triggers neurobehavioral comorbidities accompanied by relevant changes in c-Fos immunoreactivity throughout the brain.
• Necdin shapes serotonergic development and SERT activity modulating breathing in a mouse model for Prader-Willi syndrome.
• Ciliogenesis and cell cycle alterations contribute to KIF2A-related malformations of cortical development.
• Limiting habenular hyperactivity ameliorates maternal separation-driven depressive-like symptoms.
• Serotonin neuron development: shaping molecular and structural identities.
• Adaptive Control of Dorsal Raphe by 5-HT4 in the Prefrontal Cortex Prevents Persistent Hypophagia following Stress.
• RORα Coordinates Thalamic and Cortical Maturation to Instruct Barrel Cortex Development.
• Cadherin-13 Deficiency Increases Dorsal Raphe 5-HT Neuron Density and Prefrontal Cortex Innervation in the Mouse Brain.
• Genetics and mechanisms leading to human cortical malformations.
• Serotonin 2B Receptors in Mesoaccumbens Dopamine Pathway Regulate Cocaine Responses.
• Conserved rules in embryonic development of cortical interneurons.
• Molecular genetics of the transcription factor GLIS3 identifies its dual function in beta cells and neurons.
• Reactivations of emotional memory in the hippocampus-amygdala system during sleep.
• Slc7a11 (xCT) protein expression is not altered in the depressed brain and system xc- deficiency does not affect depression-associated behaviour in the corticosterone mouse model.
• Aversive stimuli drive hypothalamus-to-habenula excitation to promote escape behavior.
• Neural circuit adaptations during drug withdrawal - Spotlight on the lateral habenula.
• The BEACH Protein LRBA Promotes the Localization of the Heterotrimeric G-protein Golf to Olfactory Cilia.
• The role of 5-HT2B receptors in mitral valvulopathy: bone marrow mobilization of endothelial progenitors.
• Microglia control the glycinergic but not the GABAergic synapses via prostaglandin E2 in the spinal cord.
• Auditory cortex interneuron development requires cadherins operating hair-cell mechanoelectrical transduction.
• Loss of Dcc in the spinal cord is sufficient to cause a deficit in lateralized motor control and the switch to a hopping gait
• Mutation of the α-tubulin Tuba1a leads to straighter microtubules and perturbs neuronal migration.
• RIM1/2 in retinal ganglion cells are required for the refinement of ipsilateral axons and eye-specific segregation.
• Refining the Role of 5-HT in Postnatal Development of Brain Circuits.
• Pyk2 modulates hippocampal excitatory synapses and contributes to cognitive deficits in a Huntington's disease model.
• Heterozygous Gnal Mice Are a Novel Animal Model with Which to Study Dystonia Pathophysiology.
• Associations of the Intellectual Disability Gene MYT1L with Helix-Loop-Helix Gene Expression, Hippocampus Volume and Hippocampus Activation During Memory Retrieval.
• Specific Connectivity and Unique Molecular Identity of MET Receptor Tyrosine Kinase Expressing Serotonergic Neurons in the Caudal Dorsal Raphe Nuclei.
• Cocaine, cadherins and synaptic plasticity.
• A mutant with bilateral whisker to barrel inputs unveils somatosensory mapping rules in the cerebral cortex.
• Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons.
• Caloric Restriction Protects against Lactacystin-Induced Degeneration of Dopamine Neurons Independent of the Ghrelin Receptor.
• Heterodimers of serotonin receptor subtypes 2 are driven by 5-HT2C protomers.
• EphrinA5 Signaling Is Required for the Distinctive Targeting of Raphe Serotonin Neurons in the Forebrain.
• Serotonin transporter protects the placental cells against apoptosis in caspase 3-independent pathway.
• Zonisamide attenuates lactacystin-induced parkinsonism in mice without affecting system xc.
• Cardiovascular remodeling and the peripheral serotonergic system.
• Early born neurons are abnormally positioned in the doublecortin knockout hippocampus.
• Glutamate Counteracts Dopamine/PKA Signaling via Dephosphorylation of DARPP-32 Ser-97 and Alteration of Its Cytonuclear Distribution.
• Schwannomin-interacting Protein 1 Isoform IQCJ-SCHIP1 Is a Multipartner Ankyrin- and Spectrin-binding Protein Involved in the Organization of Nodes of Ranvier.
• Footshock-induced plasticity of GABAB signalling in the lateral habenula requires dopamine and glucocorticoid receptors.
• New therapeutic opportunities for 5-HT2 receptor ligands.
• [Pulmonary arterial hypertension, bone marrow, endothelial cell precursors and serotonin].
• Anatomical and molecular characterization of dopamine D1 receptor-expressing neurons of the mouse CA1 dorsal hippocampus.
• Electrotonic Coupling in the Pituitary Supports the Hypothalamic-Pituitary-Gonadal Axis in a Sex Specific Manner.
• Dendritic diameter influences the rate and magnitude of hippocampal cAMP and PKA transients during β-adrenergic receptor activation.
• Acute drug-induced spine changes in the nucleus accumbens are dependent on β-adducin.
• Constitutive and Acquired Serotonin Deficiency Alters Memory and Hippocampal Synaptic Plasticity.
• Shifted pallidal co-release of GABA and glutamate in habenula drives cocaine withdrawal and relapse.
• Hippocampo-cortical coupling mediates memory consolidation during sleep.
• Data in support of the identification of neuronal and astrocyte proteins interacting with extracellularly applied oligomeric and fibrillar α-synuclein assemblies by mass spectrometry.
• The Role of Synaptopodin in Membrane Protein Diffusion in the Dendritic Spine Neck.
• Assembly of juxtaparanodes in myelinating DRG culture: Differential clustering of the Kv1/Caspr2 complex and scaffolding protein 4.1B.
• Rescue of GABAB and GIRK function in the lateral habenula by protein phosphatase 2A inhibition ameliorates depression-like phenotypes in mice.
• Doublecortin (DCX) is not Essential for Survival and Differentiation of Newborn Neurons in the Adult Mouse Dentate Gyrus.
• Dopamine D2 receptors gate generalization of conditioned threat responses through mTORC1 signaling in the extended amygdala.
• Serotonin neurons in a dish.
• Serotonin 2B receptor slows disease progression and prevents degeneration of spinal cord mononuclear phagocytes in amyotrophic lateral sclerosis.
• Mice lacking the serotonin 5-HT2B receptor as an animal model of resistance to selective serotonin reuptake inhibitors antidepressants.
• Bidirectional Control of Synaptic GABAAR Clustering by Glutamate and Calcium.
• A translational systems biology approach in both animals and humans identifies a functionally related module of accumbal genes involved in the regulation of reward processing and binge drinking in males.
• Cellules souches neurales et signalisation Notch
• Pyk2 is essential for astrocytes mobility following brain lesion.
• DARPP-32 interaction with adducin may mediate rapid environmental effects on striatal neurons.
• KCC2 Gates Activity-Driven AMPA Receptor Traffic through Cofilin Phosphorylation.
• Ventral Subiculum Stimulation Promotes Persistent Hyperactivity of Dopamine Neurons and Facilitates Behavioral Effects of Cocaine.
• Multiscale single-cell analysis reveals unique phenotypes of raphe 5-HT neurons projecting to the forebrain.
• You are not alone: selecting your group members and leading an outstanding research team.
• The Catalytic Efficiency of Lipin 1β Increases by Physically Interacting with the Proto-oncoprotein c-Fos.
• Selective Effects of PDE10A Inhibitors on Striatopallidal Neurons Require Phosphatase Inhibition by DARPP-32.
• The Impact of Neuroimmune Alterations in Autism Spectrum Disorder.
• Unilateral Lesion of Dopamine Neurons Induces Grooming Asymmetry in the Mouse.
• α-synuclein assemblies sequester neuronal α3-Na+/K+-ATPase and impair Na+ gradient.
• Neuronal migration disorders: Focus on the cytoskeleton and epilepsy.
• Your ticket to independence: a guide to getting your first principal investigator position.
• Cortical interneurons migrating on a pure substrate of N-cadherin exhibit fast synchronous centrosomal and nuclear movements and reduced ciliogenesis.
• Contribution of serotonin to cardiac remodeling associated with hypertensive diastolic ventricular dysfunction in rats.
• Thalamic WNT3 Secretion Spatiotemporally Regulates the Neocortical Ribosome Signature and mRNA Translation to Specify Neocortical Cell Subtypes.
• [Contribution of synaptic release mechanisms to the building of sensory maps].
• How to awaken your nanomachines: Site-specific activation of focal adhesion kinases through ligand interactions.
• The role of primary cilia in corpus callosum formation is mediated by production of the Gli3 repressor.
• [Hell after the pleasure: drug-induced negative symptoms involve lateral habenula].
• The cytoskeleton-associated protein SCHIP1 is involved in axon guidance, and is required for piriform cortex and anterior commissure development.
• CK2-regulated schwannomin-interacting protein IQCJ-SCHIP-1 association with AnkG contributes to the maintenance of the axon initial segment.
• Mice Lacking the Serotonin Htr2B Receptor Gene Present an Antipsychotic-Sensitive Schizophrenic-Like Phenotype
• Serotonin Modulates Developmental Microglia via 5-HT2B Receptors: Potential Implication during Synaptic Refinement of Retinogeniculate Projections.
• A critical and previously unsuspected role for doublecortin at the neuromuscular junction in mouse and human.
• Dopaminergic regulation of olfactory type G-protein α subunit expression in the striatum.
• PKA-dependent phosphorylation of ribosomal protein S6 does not correlate with translation efficiency in striatonigral and striatopallidal medium-sized spiny neurons.
• Morphological and functional aspects of progenitors perturbed in cortical malformations.
• Dendritic geometry shapes neuronal cAMP signalling to the nucleus.
• Cocaine-evoked negative symptoms require AMPA receptor trafficking in the lateral habenula.
• Gene expression analyses identify Narp contribution in the development of L-DOPA-induced dyskinesia.
• [Mutations in Eml1/EML1 lead to ectopic progenitors and neuronal heterotopia in mouse and human].
• GDM-associated insulin deficiency hinders the dissociation of SERT from ERp44 and down-regulates placental 5-HT uptake.
• Conditional anterograde tracing reveals distinct targeting of individual serotonin cell groups (B5-B9) to the forebrain and brainstem.
• Conformational dynamics of the focal adhesion targeting domain control specific functions of focal adhesion kinase in cells.
• [Cilia and neuronal migrations].
• Combinatorial analysis of developmental cues efficiently converts human pluripotent stem cells into multiple neuronal subtypes.
• Attractive action of FGF-signaling contributes to the postnatal developing hippocampus.
• Brain-specific Foxp1 deletion impairs neuronal development and causes autistic-like behavior.
• Targeting the cis-dimerization of LINGO-1 with low MW compounds affects its downstream signalling
• Genetic activation of Hedgehog signaling unbalances the rate of neural stem cell renewal by increasing symmetric divisions
• Mitogen- and stress-activated protein kinase 1 is required for specific signaling responses in dopamine-denervated mouse striatum, but is not necessary for L-DOPA-induced dyskinesia.
• Humanized Foxp2 accelerates learning by enhancing transitions from declarative to procedural performance.
• Activity dependent mechanisms of visual map formation--from retinal waves to molecular regulators.
• An organotypic brain slice preparation from adult patients with temporal lobe epilepsy.
• Cilia: traffic directors along the road of cortical development.
• Division symétrique ou division asymétrique : Sonic Hedgehog contrôle le destin des cellules souches neurales adultes
• The transcription factor Fezf2 directs the differentiation of neural stem cells in the subventricular zone toward a cortical phenotype.
• MicroRNAs establish robustness and adaptability of a critical gene network to regulate progenitor fate decisions during cortical neurogenesis.
• Benzodiazepine ligands rapidly influence GABAA receptor diffusion and clustering at hippocampal inhibitory synapses.
• Long-term modifications of epileptogenesis and hippocampal rhythms after prolonged hyperthermic seizures in the mouse.
• Mutations in Eml1 lead to ectopic progenitors and neuronal heterotopia in mouse and human.
• Dampened hippocampal oscillations and enhanced spindle activity in an asymptomatic model of developmental cortical malformations.
• Hedgehog: Multiple Paths for Multiple Roles in Shaping the Brain and Spinal Cord
• Learning-induced plasticity regulates hippocampal sharp wave-ripple drive.
• Fluorescence-activated sorting of fixed nuclei: a general method for studying nuclei from specific cell populations that preserves post-translational modifications.
• The lateral habenula in addiction and depression: an anatomical, synaptic and behavioral overview.
• Reversed theta sequences of hippocampal cell assemblies during backward travel.
• Neuronal migration and its disorders affecting the CA3 region.
• FAK dimerization controls its kinase-dependent functions at focal adhesions.
• Role of the plasticity-associated transcription factor zif268 in the early phase of instrumental learning.
• Haloperidol-induced Nur77 expression in striatopallidal neurons is under the control of protein phosphatase 1 regulation by DARPP-32.
• Transcriptome sequencing during mouse brain development identifies long non-coding RNAs functionally involved in neurogenic commitment.
• N-cadherin sustains motility and polarity of future cortical interneurons during tangential migration.
• Beta tubulin isoforms are not interchangeable for rescuing impaired radial migration due to Tubb3 knockdown.
• Role of the N-terminal region in G protein-coupled receptor functions: negative modulation revealed by 5-HT2B receptor polymorphisms.
• A serotonin-induced N-glycan switch regulates platelet aggregation.
• Activity-dependent regulation of the K/Cl transporter KCC2 membrane diffusion, clustering, and function in hippocampal neurons.
• Organelle and cellular abnormalities associated with hippocampal heterotopia in neonatal doublecortin knockout mice.
• Adenosine receptor antagonists including caffeine alter fetal brain development in mice.
• Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity.
• Investigation of the proteolipid protein promoter activity during demyelination and repair
• Hippocampal development - old and new findings.
• Analysis of adult neurogenesis: evidence for a prominent "non-neurogenic" DCX-protein pool in rodent brain.
• Differential effects of cocaine on histone posttranslational modifications in identified populations of striatal neurons.
• Mutations in TUBG1, DYNC1H1, KIF5C and KIF2A cause malformations of cortical development and microcephaly.
• Molecular and functional characterization of GAD67-expressing, newborn granule cells in mouse dentate gyrus.
• Striatal neurones have a specific ability to respond to phasic dopamine release.
• Control of ALK (wild type and mutated forms) phosphorylation: specific role of the phosphatase PTP1B.
• Genetically-modified human pluripotent stem cells: new hopes for the understanding and the treatment of neurological diseases?
• GABAergic interneurons shape the functional maturation of the cortex.
• Mutation of the diamond-blackfan anemia gene Rps7 in mouse results in morphological and neuroanatomical phenotypes.
• Overexpression of 5-hydroxytryptamine 2B receptor gene in pulmonary hypertension: still a long way to understand its transcriptional regulation.
• Sonic Hedgehog signaling is a positive oligodendrocyte regulator during demyelination
• New insights into genotype-phenotype correlations for the doublecortin-related lissencephaly spectrum.
• Input-specific learning rules at excitatory synapses onto hippocampal parvalbumin-expressing interneurons.
• Tangentially migrating neurons assemble a primary cilium that promotes their reorientation to the cortical plate.
• Mutations in GNAL cause primary torsion dystonia.
• Connexin45 modulates the proliferation of transit-amplifying precursor cells in the mouse subventricular zone.
• 5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia.
• p27(Kip1) is a microtubule-associated protein that promotes microtubule polymerization during neuron migration.
• Cocaine evokes projection-specific synaptic plasticity of lateral habenula neurons.
• Expanding the spectrum of TUBA1A-related cortical dysgenesis to Polymicrogyria.
• Presynaptic but not postsynaptic GABA signaling at unitary mossy fiber synapses.
• Diffusion barriers constrain receptors at synapses.
• Vezatin is essential for dendritic spine morphogenesis and functional synaptic maturation.
• Focal adhesion kinase splice variants maintain primitive acute myeloid leukemia cells through altered Wnt signaling.
• Selective reduction of AMPA currents onto hippocampal interneurons impairs network oscillatory activity.
• The 22nd ion channel meeting, september 2011, France.
• The orphan receptor GPR3 modulates the early phases of cocaine reinforcement.
• Antinociceptive effect of peripheral serotonin 5-HT2B receptor activation on neuropathic pain.
• Genetic disruption of Pten in a novel mouse model of tomaculous neuropathy.
• Integrating neurotransmission in striatal medium spiny neurons.
• Concentration-dependent requirement for local protein synthesis in motor neuron subtype-specific response to axon guidance cues.
• Cellular anatomy, physiology and epileptiform activity in the CA3 region of Dcx knockout mice: a neuronal lamination defect and its consequences.
• Diazepam binding inhibitor promotes progenitor proliferation in the postnatal SVZ by reducing GABA signaling.
• Serotonin 5-HT2B receptors are required for bone-marrow contribution to pulmonary arterial hypertension.
• Hedgehog trafficking, cilia and brain functions
• 5-HT(2B) receptors are required for serotonin-selective antidepressant actions.
• Stimulating healthy tissue regeneration by targeting the 5-HT₂B receptor in chronic liver disease.
• Subventricular zone-derived neuroblasts use vasculature as a scaffold to migrate radially to the cortex in neonatal mice.
• "Small axonless neurons": postnatally generated neocortical interneurons with delayed functional maturation.
• Neuroscience. Synaptic switch and social status.
• Protein 4.1B contributes to the organization of peripheral myelinated axons.
• DARPP-32, Jack of All Trades… Master of Which?
• An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming.
• A human mutation in Gabrg2 associated with generalized epilepsy alters the membrane dynamics of GABAA receptors.
• The neuronal K-Cl cotransporter KCC2 influences postsynaptic AMPA receptor content and lateral diffusion in dendritic spines.
• Signaling from the cytoplasm to the nucleus in striatal medium-sized spiny neurons.
• Foxp2 regulates gene networks implicated in neurite outgrowth in the developing brain.
• The 21(st) Ion Channel Meeting, September 2010, France.
• Vascular endothelial growth factor receptor 3 directly regulates murine neurogenesis.
• Hippocampal ripples and memory consolidation.
• Labeling neuronal membrane receptors with quantum dots.
• Cholinergic influences on cortical development and adult neurogenesis.
• Neuroscience. Ubiquitination inhibits neuronal exit.
• Neurotransmitter Dynamics.
• Cyclic adenosine monophosphate-independent tyrosine phosphorylation of NR2B mediates cocaine-induced extracellular signal-regulated kinase activation.
• [Addiction: an epigenetic story of histone methylation].
• Elevated phosphatidylinositol 3,4,5-trisphosphate in glia triggers cell-autonomous membrane wrapping and myelination.
• Introduction of green fluorescent protein (GFP) into hippocampal neurons through viral infection.
• Combined microfluidics/protein patterning platform for pharmacological interrogation of axon pathfinding.
• The structure of innate vocalizations in Foxp2-deficient mouse pups.
• Generation and analysis of a mouse line harboring GFP in the Eomes/Tbr2 locus.
• Looking BAC at striatal signaling: cell-specific analysis in new transgenic mice.
• Mechanisms of locomotor sensitization to drugs of abuse in a two-injection protocol.
• Selective suppression of hippocampal ripples impairs spatial memory.
• Modified sound-evoked brainstem potentials in Foxp2 mutant mice.
• Activity-dependent tuning of inhibitory neurotransmission based on GABAAR diffusion dynamics.
• A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice.
• Pten deletion in adult neural stem/progenitor cells enhances constitutive neurogenesis.
• Two novel CLCN2 mutations accelerating chloride channel deactivation are associated with idiopathic generalized epilepsy.
• Xenotransplantation of embryonic stem cell-derived motor neurons into the developing chick spinal cord.
• Modes and mishaps of neuronal migration in the mammalian brain.
• A functional genetic link between distinct developmental language disorders.
• Tumor suppressor schwannomin/merlin is critical for the organization of Schwann cell contacts in peripheral nerves.
• The T-box transcription factor Eomes/Tbr2 regulates neurogenesis in the cortical subventricular zone.
• The location of DCX mutations predicts malformation severity in X-linked lissencephaly.
• Neuropathological phenotype of a distinct form of lissencephaly associated with mutations in TUBA1A.
• Homeostatic regulation of synaptic GlyR numbers driven by lateral diffusion.
• Prenatal activation of microglia induces delayed impairment of glutamatergic synaptic function.
• Epilepsy in Dcx knockout mice associated with discrete lamination defects and enhanced excitability in the hippocampus.
• A phosphatase cascade by which rewarding stimuli control nucleosomal response.
• DARPP-32: molecular integration of phosphorylation potential.
• GABA(A) receptor gamma 2 subunit mutations linked to human epileptic syndromes differentially affect phasic and tonic inhibition.
• Nocodazole-induced changes in microtubule dynamics impair the morphology and directionality of migrating medial ganglionic eminence cells.
• The GTP-binding protein Rhes modulates dopamine signalling in striatal medium spiny neurons.
• Conserved pattern of tangential neuronal migration during forebrain development.
• Large spectrum of lissencephaly and pachygyria phenotypes resulting from de novo missense mutations in tubulin alpha 1A (TUBA1A).
• How can drug discovery for psychiatric disorders be improved?.
• Modified receptor internalization upon coexpression of 5-HT1B receptor and 5-HT2B receptors.
• Single quantum dot tracking of membrane receptors.
• Magnetic resonance imaging and histological studies of corpus callosal and hippocampal abnormalities linked to doublecortin deficiency.
• Microglial control of neuronal death and synaptic properties.
• PGY repeats and N-glycans govern the trafficking of paranodin and its selective association with contactin and neurofascin-155.
• Quantitative changes in Galphaolf protein levels, but not D1 receptor, alter specifically acute responses to psychostimulants.
• The role of sleep in emotional processing: insights and unknowns from rodent research.
• Laminar and compartmental regulation of dendritic growth in mature cortex.
• Role of the neuronal K-Cl co-transporter KCC2 in inhibitory and excitatory neurotransmission.
• Serotonin 2B receptor (5-HT2B R) signals through prostacyclin and PPAR-ß/δ in osteoblasts.

Séminaires

• Antonia WIEGERING
• Jianping FU
• Eline MERTENS
• Maithe ARRUDA-CARVALHO
• David BENSIMON
• Jesse VEENVLIET
• Kim YONG
• Silvia CAPPELLO
• Hynek WICHTERLE
• Andrew McASKIL
• Marine KRZISCH
• Liset MENENDEZ DE LA PRIDA
• William AMOYAL
• Fadel TISSIR
• Elodie PERRIN
• Christophe FLEURY
• Victor CAZARES
• Laurent NGUYEN
• Ana UZQUIANO
• Bhavana MURALIDHARAN
• Sara XAPELLI
• Mariano SOIZA-REILLY
• Marina PICCIOTTO
• Charlotte BOCCARA
• Emmanuel VALJENT
• Astrid CHEVANCE
• Julia FUCHS
• Belen PARDI
• Bryan SOUZA
• Alan KAY
• William AMOYAL
• Stefan T. AROLD
• Sylvie GRANON
• Gaia NOVARINO
• Olivier PETITJEAN
• Marine SALERY
• Xavier NICOL
• Esther KLINGLER
• Stéphane AUVIN
• Luisa LOPES
• Yasmine CANTAUT-BELARIF
• Guillemette CREPEAUX
• Juliette GODIN
• Martine COHEN-SALMON
• Rejane RUA
• Yves DE KONINCK
• Antoine ZALC
• Isabelle BRUNET
• Niels NIETHARD
• Frédéric CAUSERET
• Gregory GAUVAIN
• Diane DAMEZ-WERNO
• Sara BIZZOTO
• Tamara CASPARY
• Iris SALECKER
• Diego GARCIA-GONZALEZ
• Laure BAILLY-CUIF
• Mari SOSA
• Gaël MALLERET
• Germán SUMBRE
• Sandrine BETUING
• Anna TERNON
• Lukas TAMAYO ORREGO
• Volker BORMUTH
• Vincent MAGLOIRE
• Maëva LUXEY
• Marina PICCIOTTO
• Lucile MARION-POLL
• Félix LEROY
• François TRONCHE
• Chin EAP
• Gilles FISCHER
• Sylvie SCHEINDER-MAUNOURY
• Stéphanie BAULAC
• Luigi BELLOCCHIO
• Paul VEZINA
• David DUPRET
• Anass TINAKOUA
• Bassem HASSAN
• Esther STOECKLI
• Huttner WIELAND
• Séverine CHAUMONT-DUBEL
• Maxime ASSOUS
• Morgane BELLE
• Carol MARCHETTO
• Nathalie ROUACH
• David BLUM
• Rustem KHAZIPOV
• Gisella VETERE
• Laurent VENANCE
• Philippe FAURE
• Vincent PASCOLI
• Shubha TOLE

Actualités

• Journée des Jeunes Chercheurs à l'IFM, 6ème édition !
• Colloque IFM 2024 "Signals and Circuits for Motivation and Movement"
• Chaire de Professeur Junior en Neurogénomique/neurogénétique
• 20ème journée du Club Développement des Réseaux Neuronaux
• Prix Brixham Foundation 2023
• Colloque international “Neuroimmunity, Development & Psychiatry”
• Journée des Jeunes Chercheurs à l'IFM, 5ème édition !
• L'IFM recrute un(e) zootechnicien(ne) statutaire !
• Journée inter-UFR 'Biologie & Ingénierie', Sorbonne Université
• Colloque international “Epi/genetic architecture of psychiatric disorders”
• Journée des Jeunes Chercheurs à l'IFM, 4ème édition !
• Appel à candidature pour la direction du nouvel Institut de Biologie de Sorbonne Université
• C-BRAINS: un réseau régional de recherche et d'innovation en Neurosciences et Sciences Cognitives
• l'IFM se prépare pour le FENS Forum 2022 à Paris !
• Séminaire décalé IBPS - 26 Novembre 2021
• Mini symposium : AI and data science for biology
• i-Bio, pour la recherche interdisciplinaire en biologie : rétrospective des 18 premiers mois et perspectives
• Appel à candidatures pour la direction d'i-Bio
• L’IFM recrute un Professeur de Biologie du Développement
• Edition 2021 du programme doctoral i-Bio
• Les séminaires hebdomadaires reprennent à l'IFM
• i-Bio, une initiative pour la recherche interdisciplinaire en Sciences de la Vie à Sorbonne Université
• International symposium of the IFM and NPS – “The Sleeping Brain”
• Network of Young Researchers Neuro-Day

Templates

• Séminaire en ligne

Equipes

• Girault
• Francis / Goutebroze
• Poncer
• Métin
• Roumier / Le Magueresse
• Girardeau
• Nedelec
• Ferent
• Groszer

Par équipe

• Ferent
• Francis / Goutebroze
• Gaspar
• Girardeau
• Girault
• Groszer
• Mameli
• Maroteaux / Roumier
• Métin
• Nedelec
• Plateforme Imagerie
• Poncer

Statut

• A venir
• Mis en Avant
• Passé

Types d'Actualités

• Colloques
• Evenements